Dental Health

Dentistry in Stem Cell Regeneration and Repair

Stem cells are undifferentiated cells elucidated by two distinct characteristics, namely, their ability to continuously self-renew and to differentiate into multiple mature cell types. Stem cells are significant because one somatic cell has the potential to function as an inexhaustible proliferative source for replacement therapy, comprising one component of the tissue engineering triad. Stem cells are often categorized as embryo genic stem cells (ESCs) or adult stem cells consistent with the stage at which they're isolated.

Various types of tooth derived stem cells have been utilized in the field of regeneration medicine. Tooth derived stem cells or dental stem cells are categorized consistent with the situation from which they're isolated and represent a promising source of cells for regenerative medicine. Originally, as one kind of mesenchymal stem cells, they're considered an alternate of bone marrow stromal cells. They share many commonalties but maintain differences. Considering their original function in development and therefore the homeostasis of tooth structures, many applications of those cells in dentistry have aimed toward tooth structure regeneration.

The availability from discarded or removed teeth are often an innate benefit as a source of autologous cells. Their origin from the neural crest leads to exploitation of neurological and various other applications.

Dental Pulp Stem Cells (DPSCs)

Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs)

Periodontal Ligament Stem Cells (PDLSCs)

Stem Cells from Apical Papilla (SCAPs)

Dental Follicle Progenitor Cells (DFPCs)